By Atta-ur-Rahman

This enormous tome through Prof. Atta-ur-Rahman and Dr. Zahir Shah pres ents a wide total point of view of stereo selectivity within the synthesis of or ganic molecules. therefore it treats an issue that's of primary significance and should be much more very important sooner or later because the drug is needed to provide 1000/0 optically natural compounds. After an exposition of normal rules, the subsequent matters are handled: Catalytic rate reductions, Heterogeneous Catalytic Hydrogenations, Stereoselective Non-Catalytic mark downs, Stereos non-obligatory Carbon-Carbon Bond Forming Reactions, uneven Oxidations, uneven Carbon Heteroatom Bond Formations, Enzyme Catalyzed Reactions, Stereo selective loose Radical Reactions, and at last Miscellaneous Stereoselective Reactions. for every topic, a wealth of examples are given. The hugely selective reactions are pointed out in addition to reactions that aren't. this is often useful because it will train the sensible chemist what to prevent. a lot development has been made within the final 20 years within the layout of latest, very stereoselective reactions which are utilized in undefined. for instance, and in alphabetical order, we will point out (among different peers): H.C. Brown (hydroboration), D.C. Evans (carbon-carbon bond forma tion), R. Noyori (BINAP reagents for hydrogenation), and K.B. Sharpless (epoxidation and dihydroxylation of double bonds). hence the sphere has thoroughly replaced because the Nineteen Fifties, whilst optically natural compounds have been continually acquired through tricky resolutions of racemates and never through stereoselec tive reactions.